23 2019 INTEGRATED SUMMARY REPORT Humalog List and Net Price Per Vial4 Average Lilly Net Price (As a % of List Price) After Discounts Across the U.S. Product Portfolio5 Humalog List Price Per Vial Insulin Lispro List Price Per Vial Humalog/Insulin Lispro Net Price Per Vial $268 $275 $275 $246 55% $216 $137 50% 49% 46% 43% $70 $59 $61 $62 $60 2015 2016 2017 2018 2019 2015 2016 2017 2018 2019 The last list price increase for Humalog vial was May 2017. The net price in the chart represents the revenue Lilly realized per Humalog and Insulin Lispro vial after rebates and discounts. Increases in list prices do not always create increases in net prices. 4. The average net price per vial, the amount Lilly receives after rebates and discounts, is calculated by dividing the total net vial sales (Humalog and Insulin Lispro vials), by the total vials sold. 5. The average net price percentage is calculated by dividing net sales, the amount Lilly receives after rebates and discounts, by the annual gross sales (total sales at list price, prior to all discounts). Average Cost of Humalog Prescriptions Filled at Retail Pharmacies6 (2017 data) $0 $1 - 95 $96+ 0% 25% 50% 75% 100% 6. Humalog is the most broadly used Lilly insulin product. FREE INSULIN LILLY DIABETES SOLUTION CENTER Lilly also donates medicines to charitable organizations that People who use Lilly insulin can learn about all options provide free medicine, including insulin, to patients meeting program that may reduce their out-of-pocket costs by calling the eligibility requirements. In the last five years, Lilly has donated more Lilly Diabetes Solution Center. than 7 million insulin vials and pens to U.S. charitable organizations, Medical representatives are including Americares, Direct Relief, Dispensary of Hope and available at (833) 808-1234. the Lilly Cares Foundation®.